A post-analysis of the SAVOR-TIMI 53 trial and a review of 17 different observational studies showed metformin use is associated with decreased all-cause mortality in people with type 2 diabetes and a high risk of cardiovascular events.
In a previous systematic review of 17 observational studies published in the Annals of Internal Medicine in 2017, researchers concluded that metformin use is associated with decreased all-cause mortality in patients with CKD, congestive heart failure, or chronic liver disease with hepatic impairment.
Find out more details about the Harvard Medical School study here.
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