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Rationale of the Week | Do Statins Cause Dementia?

For last week’s practice question, we quizzed participants on statins & the risk of dementia. 49% of respondents chose the best answer. We want to clarify and share this important information, so you can pass it on to people living with diabetes and your colleagues, plus prepare for exam success!

Before we start though, if you don’t want any spoilers and haven’t tried the question yet, you can answer it below: Answer Question

Question: LR is 78 years old with a new diagnosis of diabetes. Their A1C is 7.9%, LDL cholesterol is 98 mg/dL, GFR is 58 mg/g and their BP is 124/78. The provider recommends a referral to the RD and DSME program and writes a prescription for metformin XR 500mg daily and lovastatin 20mg. LR is worried about taking a statin because they heard it can cause dementia.

Based on the ADA Standards, what is the best response?

Answer Choices:

  1. Based on the most recent research, statins don’t seem to cause dementia.
  2. Statins are very safe and actually protect against dementia.
  3. To find out more about the side effects of statins, we recommend asking your pharmacist for more information.
  4. You can start with half a pill a day to evaluate for side effects.

Getting to the Best Answer

If you are thinking about taking the certification exam, this practice test question will set you up for success. Test writers anticipate possible answers based on the details in the question. They will wave those “juicy answers” right under your nose. Your job is to weed through the particulars, pluck out the most important elements and choose the BEST answer.

Answer 1 is correct. 49.45% chose this answer. “Based on the most recent research, statins don’t seem to cause dementia.” YES, is the BEST answer. According to ADA 2023 SOC 10 a recent systematic review of the U.S. Food and Drug Administration’s (FDA’s) postmarketing surveillance databases, randomized controlled trials, and cohort, case-control, and cross-sectional studies evaluating cognition in patients receiving statins found that published data do not reveal an adverse effect of statins on cognition (138). Therefore, a concern that statins or other lipid-lowering agents might cause cognitive dysfunction or dementia is not currently supported by evidence and should not deter their use in individuals with diabetes at high risk for ASCVD (138).

Answer 2 is incorrect. 26.73% of you chose this answer. “Statins are very safe and actually protect against dementia.” Although the first part of this statement is correct, statins are safe, there is no evidence presented in the ADA Standards that statins protect against dementia.

Answer 3 is incorrect. About 17.62% of respondents chose this. “To find out more about the side effects of statins, we recommend asking your pharmacist for more information.” Although pharmacists are incredibly knowledgeable about medications, diabetes specialists can relate evidence based information to the people we serve, instead of making them take additional action to get the information they need to move forward. The good news is that there is no evidence that statins or other lipid-lowering agents might cause cognitive dysfunction or dementia and their use is recommended in individuals with diabetes at high risk for ASCVD.

Finally, Answer 4 is incorrect. 6.19% chose this answer. “You can start with half a pill a day to evaluate for side effects.” This approach is tempting, but it doesn’t address the fear of the statin causing dementia. The good news is that there is no evidence that statins or other lipid-lowering agents might cause cognitive dysfunction or dementia and their use is recommended in individuals with diabetes at high risk for ASCVD.

We hope you appreciate this week’s rationale! Thank you so much for taking the time to answer our Question of the Week and participate in this fun learning activity!


Want to learn more about this question? Enroll in our

Level 2 | Older Adults & Diabetes | 1.5 CEs

 

We are living longer & more people are getting diabetes. The American Diabetes Association has updated the Older Adults Standards, with special attention to considering the reduction of medication & insulin therapy intensity. The older population has unique issues & special needs that require consideration as we provide diabetes self-management education. This online course highlights key areas of assessment, intervention, and advocacy for older clients living with diabetes.

Objectives:

  1. Self-management considerations for older individuals.
  2. Strategies to prevent complications & maintain optimal quality of life.
  3. The role of the Diabetes Care & Education Specialist as an advocate.

Intended Audience: An important course for healthcare professionals seeking to gain an understanding of the special issues and goals for older adults.

Don’t worry if you can’t make it live. Your registration guarantees access to the recorded version in the Online University.

All hours earned count toward your CDCES Accreditation Information


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The use of DES products does not guarantee the successful passage of the CDCES exam. CBDCE does not endorse any preparatory or review materials for the CDCES exam, except for those published by CBDCE.

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The use of DES products does not guarantee the successful passage of the certification exam. CBDCE and ADCES do not endorse any preparatory or review materials for the CDCES or BC-ADM exams, except for those published by CBDCE & ADCES.

**To satisfy the requirement for renewal of certification by continuing education for the Certification Board for Diabetes Care & Education (CBDCE), continuing education activities must be applicable to diabetes and approved by a provider on the CBDCE List of Recognized Providers (www.cbdce.org). CBDCE does not approve continuing education. Diabetes Education Services is accredited/approved by the Commission of Dietetic Registration which is on the list of CBDCE Recognized Providers.

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