
For last week’s practice question, we quizzed participants on being at risk for NASH. 63% of respondents chose the best answer. We want to clarify and share this important information, so you can pass it on to people living with diabetes and your colleagues, plus prepare for exam success!
Before we start though, if you don’t want any spoilers and haven’t tried the question yet, you can answer it below: Answer Question
Question: JR is 46 years old with type 2 diabetes and a BMI of 33. In addition, JR has hypertension and hyperlipidemia, with elevated liver enzymes (ALT and AST).
According to the latest ADA Standards, which of the following would best help determine if JR is at risk for liver fibrosis and cirrhosis?
Answer Choices:
- UACR
- FIB-4
- GAD or ICA
- Weight in (kg) divided by the square of height in meters (m2)

Getting to the Best Answer
If you are thinking about taking the certification exam, this practice test question will set you up for success. Test writers anticipate possible answers based on the details in the question. They will wave those “juicy answers” right under your nose. Your job is to weed through the particulars, pluck out the most important elements and choose the BEST answer.
Answer 1 is incorrect. 14.51% chose this answer. “UACR.” This is a juicy answer, however the Urinary Albumin Creatinine Ratio (UACR) evaluates kidney function and doesn’t provide any hepatic insights. Instead we would recommend the Fibrosis-4 Index for Liver Fibrosis helps determine risk of hepatic cirrhosis and inflammation (see answer 2).
Answer 2 is correct. 62.53% of you chose this answer. “FIB-4.” GREAT JOB. The Fibrosis-4 Index for Liver Fibrosis helps determine risk of hepatic cirrhosis and inflammation. By entering the person’s age, AST, ALT and Platelet count using the FIB-4 calculator, a risk level is calculated (see slide below). The hope is that by screening for hepatic issues early, we can take action to protect the liver and improve outcomes.
Answer 3 is incorrect. About 11.69% of respondents chose this. “GAD or ICA.” Although this answer is familiar, it does not match the intent of the question. GAD and ICA are blood tests to determine if someone has autoimmune mediated type 1 diabetes. Instead we would recommend the Fibrosis-4 Index for Liver Fibrosis helps determine risk of hepatic cirrhosis and inflammation (see answer 2).
Finally, Answer 4 is incorrect. 11.27% chose this answer. “Weight in (kg) divided by the square of height in meters (m2).” This answer is also familiar since it is the formula to determine a person’s body mass index (BMI). Instead we would recommend the Fibrosis-4 Index for Liver Fibrosis helps determine risk of hepatic cirrhosis and inflammation (see answer 2).
We hope you appreciate this week’s rationale! Thank you so much for taking the time to answer our Question of the Week and participate in this fun learning activity! Learn more by attending our Virtual Conference plus save $100 through April 18, 2023.

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