Gastric Bypass Surgery associated with high type 2 diabetes remission rates

A recent study conducted by the Aarhus University Hospital in Denmark found that three out of every four persons living with obesity and type 2 diabetes who receive a RYGB ( Roux-en-Y Gastric Bypass) experience remission within one year. Remission is defined as blood glucose levels at non-diabetes range without using diabetes medications.

This study followed 1,111 individuals who had an elevated BMI and type 2 diabetes and underwent RYGB from 2006-2015. It also followed 1,074 individuals who also had an elevated BMI with type 2 diabetes but did not undergo the surgery.

The results of this study for people with type 2 and a BMI of 35 or greater who had RYGB:

  • 74% of individuals experienced diabetes remission within one year
  • 27% of these individuals relapsed after approximately five years.
  • Those less likely to experience diabetes remission included:
    – those over 50,
    – diabetes duration > 5 years,
    – use of glucose lowering drugs other than metformin
    – baseline A1c of more than 7%

In addition, those who had RYGB surgery had a significantly reduced risk of microvascular and possibly macrovascular complications compared to those who did not have surgery.

According to the authors of the study, RYGB is associated with a high remission rate and a decreased rate of vascular complications, especially if surgery in performed early after diabetes diagnosis.

See chart in article by clicking on image

For more information on this topic, read the full study in Diabetologia- Effect of Roux-en-Y gastric bypass surgery on diabetes remission and complications in individuals with type 2 diabetes: a Danish population-based matched cohort study.


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