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Type 5 Diabetes

By: Beverly Thomassian

A newly recognized form of diabetes, termed Type 5 diabetes, has been officially acknowledged by the International Diabetes Federation (IDF). This condition, also known as malnutrition-related diabetes, primarily affects lean and undernourished teenagers and young adults in low- and middle-income countries (LMICs), particularly in regions such as Asia and Africa. Unlike Type 1 and Type 2 diabetes, Type 5 diabetes is primarily caused by chronic undernutrition, especially during childhood or adolescence, leading to impaired pancreatic development and insufficient insulin production.The Sun+1The Independent+1Medscape+5idf.org+5Esteve Pharma+5

Historically, this condition was often misclassified as Type 1 or Type 2 diabetes, leading to inappropriate treatment strategies. Patients with Type 5 diabetes are insulin-deficient but not insulin-resistant, distinguishing them from those with Type 2 diabetes. Moreover, they do not develop ketonuria or ketosis despite high blood glucose levels, setting them apart from Type 1 diabetes patients.idf.orgMedscape

The formal recognition of Type 5 diabetes by the IDF in April 2025 marks a pivotal moment in the understanding of diabetes and its diverse manifestations. This acknowledgment is expected to accelerate research, improve diagnosis, and lead to the development of tailored treatment approaches for this overlooked condition .​The Independent+5idf.org+5Diabetes+5

For more information on Type 5 diabetes, you can refer to the IDF’s announcement: idf.org.

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