We have two updates to announce that have been captured in our electronic Medication PocketCards.

Saxagliptin Discontinued

The DPP-IV Inhibitor Saxagliptin (Onglyza) and combination medication, Kombiglyze XR (saxagliptin/metformin extended-release tablets), have been permanently discontinued, according to manufacturer AstraZeneca.

A recent posting on the Food and Drug Administration’s (FDA) Drug Shortages tracker indicates that both products were discontinued because of a business decision and not due to safety or efficacy-related concerns.

There are three other DPP-IV inhibitors still available along with several combination versions. See our updated electronic ePocketCard that reflects this update.

Dulaglutide Approved for Peds

In late 2022, the FDA approved the use of Dulaglutide (Trulicity for Pediatrics with Type 2 diabetes ages 10-17. Currently, metformin, insulin and the following GLP-1 RA’s are approved for pediatrics with type 2 diabetes, ages 10-17 See updated ePocketCard.

GLP-1 RA list of approved medications for pediatrics.

• Exenatide XR (Bydureon)
• Liraglutide (Victoza)
• Dulaglutide (Trulicity) up to 1.5mgs

GLP-1 RAs have the benefit of not only lowering A1C, they also support weight loss and Exenatide XR and dulaglutide only need to be taken once a week. This weekly dosing can be a big advantage for busy families.

Our currently available laminated Diabetes Med PocketCards do not reflect these changes, but we will be reprinting later this year to reflect these updates.

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