Hybrid Insulin Pump Use Lowers A1c

The MiniMed 670G is the first FDA approved closed loop insulin delivery system. The pump in combination with a glucose sensor, provides and adjusts basal insulin based on an internal algorithm coupled with continuous glucose readings. This system has an added safety feature of suspending insulin delivery before blood sugars take a dive into dangerous territory.

Real world data is now being collected to evaluate user satisfaction and clinical outcomes. And the findings are positive, according to researcher Lisa T. Meade, PharmD, CDE, professor of pharmacy at Wingate University in North Carolina.

Her research included a retrospective chart audit of adults with type 1 who used the Medtronic MiniMed 670G. The study evaluated A1c, time in range and user satisfaction. Of these, 33 participants completed a satisfaction survey after at least three months of use.

A1c Results
Based on the chart audit results, the average A1c in the study group dropped significantly. At six months it dropped by 0.9% vs. baseline (P=.015). At one year, the A1c dropped by 1.2% (P=.001) vs. baseline.

Time-In-Range and Satisfaction results
Based on the survey, the average satisfaction score was 3.79 (score range 1-5). These participants also experienced time-in-range benefits.

According to Meade, “We were encouraged with the mean time in range of 67%, but we also see room for improvement. The American Diabetes Association recommends the people using CGMs spend at least 70% of their time between 70 mg/dL and 180 mg/dL. Meade concluded that “The study did confirm the need for better office procedures to track patients starting on new technology and to ensure regular follow-up visits.”


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References:

Healio Endocrine Today – Aug 10. 2019

Meade LT, et al. P811. Presented at: American Association of Diabetes Educators; Aug. 9-12, 2019; Houston.

Disclosure: Meade reports she is a certified pump trainer for Medtronic.