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Question of the Week | Which Treatment is FDA Approved for MASH?

Question of the Week Diabetes Education Services

MJ just discovered that in addition to their type 2 diabetes and a BMI of 31, they also have MASH. 

Based on this diagnosis, which FDA approved medication would help address their steatosis?

  1. Semaglutide (Ozempic)
  2. Empagliflozin (Jardiance)
  3. Tirzepatide (Mounjaro)
  4. Semaglutide (Wegovy)

Invite a colleague to our DiabetesEd Seminar in San Diego and get $75 off each registration.

Use code FriendDiscountSD during check to save. 

Join us live in San Diego October 22nd – 23rd, 2025 for our upcoming

DiabetesEd Training Seminar

Earn 30+ CEs with Expanded Accreditation!

Join our expert team for engaging, interactive sessions that bring the ADA Standards of Care to life—covering medications, behavior change, technology, and more. Ideal for CDCES or BC-ADM exam prep, this course also includes a 4-hour Virtual Medical Nutrition Therapy Toolkit and bonus content that also meets CDCES renewal requirements.

Program Objectives:

Upon completion of this activity, participants should be able to:

  • Describe the current ADA Standards for diagnosis, goals, and person-centered diabetes management across the lifespan. 
  • Demonstrate insulin pattern management and dosing strategies in clinical scenarios.
  • Implement timely screening and risk reduction strategies for microvascular and cardiovascular complications.  
  • Incorporate behavior change techniques and medical nutrition therapy to support people with diabetes self-management and lifestyle adjustment.  

Expert Faculty:

Diana Isaacs, PharmD, BCPS, BCACP, CDCES, BC-ADM, FADCES, FCCPCES

Smiling woman in white blazer and lavender blouse

Beverly Thomassian, RN, MPH, CDCES, BC-ADM

Faculty Bios & Disclosures

Our expert team transforms complex diabetes science into clear, practical insights—keeping it real, engaging, and fun!

Program Faculty Disclosures:

Partners for Advancing Clinical Education (Partners) requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Partners policies. Others involved in the planning of this activity have no relevant financial relationships.

Faculy Bios & Disclosures:

Coach Beverly Thomassian RN, MPH, CDCES, BC-ADM – CEO of DiabetesEd Services

Disclosures: 

Beverly Thomassian has no financial disclosures

Bio:

Author, Nurse, Educator, Clinician, and Innovator, Beverly has specialized in diabetes management for over twenty years. As president and founder of Diabetes Education Services, Beverly is dedicated to providing compassionate and evidence based diabetes education and improving the lives of those with diabetes.

PicsArt_04 03 11Diana Isaacs, PharmD, BCPS, BCACP, CDCES, BC-ADM, FADCES, FCCPCES 

Disclosures:

Dr. Diana Isaacs has the following relevant financial relationships:

  • Consultant, advisor, and speaker for Abbot Labratories, Dexcom, Medtronic, Insulet, Lilly, Cequr, Sanofi, and Undermyfork
  • Board member at Association for Diabetes Care and Education Specialists

Bio:

Diana Isaacs was awarded 2020 ADCES Diabetes Educator of the Year for her educational platform promoting the use of CGM for people with diabetes and other innovations.  She serves in leadership roles for several pharmacies and diabetes organizations. She has numerous diabetes publications and research projects with a focus on medications, CGM and diabetes technology.

For the past three year, Dr. Isaacs has served as a contributing author for the 2023 ADA Standards of Care.

As the Program Coordinator and clinical pharmacist specialist in the Cleveland Clinic Diabetes Center, Dr. Isaacs brings a wealth of clinical knowledge combined with extensive research and speaking experience to this program. 

Activity Start and End Date: 10/22/25 – 10/23/2025

Estimated time to complete the activity: 15 hours and 30 minutes

_____________________________________

Jointly provided by Partners for Advancing Clinical Education and Diabetes Education Services



Joint Accreditation Statement:

 In support of improving patient care, this activity has been planned and implemented by Partners for Advancing Clinical Education (Partners) and Diabetes Education Services. Partners is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Education:

Partners designates this enduring material for a maximum of 15.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development:

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 15.50 contact hours.

Pharmacy Continuing Education:

Partners designates this continuing education activity for 15.50 contact hour(s) (1.550 CEUs) of the Accreditation Council for Pharmacy Education.
(Universal Activity Number – JA4008073-9999-25-206-L01-P)
Type of Activity: Application

For Pharmacists: Upon successfully completing the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 4 weeks.

Dietitian Continuing Education:

This program offers 15.50 CPEUs for dietitians.

Interprofessional Continuing Education:

This activity was planned by and for the healthcare team, and learners will receive 15.50 Interprofessional Continuing Education (IPCE) credit for learning and change.

For additional information about the accreditation of this activity, please visit https://partnersed.com.

The use of DES products does not guarantee the successful passage of the certification exam. CBDCE and ADCES do not endorse any preparatory or review materials for the CDCES or BC-ADM exams, except for those published by CBDCE & ADCES.

October 2025 eNews

Happy October!💚

Greetings, wonderful healthcare colleagues!

With the onset of fall, it is the perfect time to curl up with a good book and read our monthly newsletter. Pull out your calendar and save the dates for our upcoming courses and free webinars.

First up, you are going to do a happy dance when you download our GLP-1/GIP Indications Cheat Sheet. With a glance, you will be able to quickly determine which incretin is the best match for the person sitting across from you, considering their glucose levels, weight goals, age, and other co-conditions. Shout out to Diana Issacs, PharmD, CDCES, for getting the ball rolling on this latest addition to our Cheat Sheet Library.

Speaking of Diana Isaacs, you won’t want to miss her at our DiabetesEd Course in San Diego in a few weeks. We have so much fun co-teaching at this conference and giving attendees our full attention! Invite a friend, save $75, and get ready for a wonderful experience and a comprehensive diabetes update.

Over 60% of people with diabetes are living with liver steatosis. Our nutrition expert, Christine Craig, reviews evidence-based lifestyle approaches that you can quickly apply in your clinical practice.

If you are looking for an easy-to-use insulin delivery device, check out this review article on CeQur Simplicity by our tech expert, Dr. Sarah Beattie. She explores the benefits and limitations of this straightforward bolus insulin delivery device.

A big welcome to our newest team member and customer service advocate, Astraea Ballinger. They bring a wealth of experience and positive energy to the team, and we are thrilled to introduce them.

Test your knowledge with our question and rationale of the week, and we hope to see you in San Diego!

With appreciation,

Coach Beverly, Bryanna, Astraea & Katarina

Save $75 – Invite a colleague to our DiabetesEd Seminar in San Diego.

Use code FriendDiscountSD during checkout to save!

Join us live in San Diego October 22nd - 23rd, 2025 for our upcoming

DiabetesEd Training Seminar

30+ CEs with Expanded Accreditation!

Join our expert team for engaging, interactive sessions that bring the ADA Standards of Care to life—covering medications, behavior change, technology, and more. Ideal for CDCES or BC-ADM exam prep, this course also includes a 4-hour Virtual Medical Nutrition Therapy Toolkit and bonus content that also meets CDCES renewal requirements.

Program Objectives:

Upon completion of this activity, participants should be able to:

  • Describe the current ADA Standards for diagnosis, goals, and person-centered diabetes management across the lifespan. 
  • Demonstrate insulin pattern management and dosing strategies in clinical scenarios.
  • Implement timely screening and risk reduction strategies for microvascular and cardiovascular complications.  
  • Incorporate behavior change techniques and medical nutrition therapy to support people with diabetes self-management and lifestyle adjustment.  

Expert Faculty:

Diana Isaacs, PharmD, BCPS, BCACP, CDCES, BC-ADM, FADCES, FCCPCES

Smiling woman in white blazer and lavender blouse

Beverly Thomassian, RN, MPH, CDCES, BC-ADM

Faculty Bios & Disclosures

Our expert team transforms complex diabetes science into clear, practical insights—keeping it real, engaging, and fun!

Program Faculty Disclosures:

Partners for Advancing Clinical Education (Partners) requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Partners policies. Others involved in the planning of this activity have no relevant financial relationships.

Faculy Bios & Disclosures:

Coach Beverly Thomassian RN, MPH, CDCES, BC-ADM – CEO of DiabetesEd Services

Disclosures: 

Beverly Thomassian has no financial disclosures

Bio:

Author, Nurse, Educator, Clinician, and Innovator, Beverly has specialized in diabetes management for over twenty years. As president and founder of Diabetes Education Services, Beverly is dedicated to providing compassionate and evidence based diabetes education and improving the lives of those with diabetes.

PicsArt_04 03 11Diana Isaacs, PharmD, BCPS, BCACP, CDCES, BC-ADM, FADCES, FCCPCES 

Disclosures:

Dr. Diana Isaacs has the following relevant financial relationships:

  • Consultant, advisor, and speaker for Abbot Labratories, Dexcom, Medtronic, Insulet, Lilly, Cequr, Sanofi, and Undermyfork
  • Board member at Association for Diabetes Care and Education Specialists

Bio:

Diana Isaacs was awarded 2020 ADCES Diabetes Educator of the Year for her educational platform promoting the use of CGM for people with diabetes and other innovations.  She serves in leadership roles for several pharmacies and diabetes organizations. She has numerous diabetes publications and research projects with a focus on medications, CGM and diabetes technology.

For the past three year, Dr. Isaacs has served as a contributing author for the 2023 ADA Standards of Care.

As the Program Coordinator and clinical pharmacist specialist in the Cleveland Clinic Diabetes Center, Dr. Isaacs brings a wealth of clinical knowledge combined with extensive research and speaking experience to this program. 

Activity Start and End Date: 10/22/25 – 10/23/2025

Estimated time to complete the activity: 15 hours and 30 minutes

_____________________________________

Jointly provided by Partners for Advancing Clinical Education and Diabetes Education Services



Joint Accreditation Statement:

 In support of improving patient care, this activity has been planned and implemented by Partners for Advancing Clinical Education (Partners) and Diabetes Education Services. Partners is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Education:

Partners designates this enduring material for a maximum of 15.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development:

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 15.50 contact hours.

Pharmacy Continuing Education:

Partners designates this continuing education activity for 15.50 contact hour(s) (1.550 CEUs) of the Accreditation Council for Pharmacy Education.
(Universal Activity Number – JA4008073-9999-25-206-L01-P)
Type of Activity: Application

For Pharmacists: Upon successfully completing the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 4 weeks.

Dietitian Continuing Education:

This program offers 15.50 CPEUs for dietitians.

Interprofessional Continuing Education:

This activity was planned by and for the healthcare team, and learners will receive 15.50 Interprofessional Continuing Education (IPCE) credit for learning and change.

For additional information about the accreditation of this activity, please visit https://partnersed.com.

The use of DES products does not guarantee the successful passage of the certification exam. CBDCE and ADCES do not endorse any preparatory or review materials for the CDCES or BC-ADM exams, except for those published by CBDCE & ADCES.

Rationale of the Week | Grandfather Avoiding Bolus Insulin

For last week’s practice question, we quizzed participants on insulin. 96% of respondents chose the best answer. We want to clarify and share this important information, so you can pass it on to people living with diabetes and your colleagues, plus prepare for exam success!

Before we start though, if you don’t want any spoilers and haven’t tried the question yet, you can answer it below: Answer Question

Lightbulb and text: Rationale of the Week

R.S. is a 60-year-old with type 2 diabetes who was recently placed on insulin lispro at meals.  He has taken insulin glargine once a day for five years. Previously, non-insulin medications have been ineffective or not tolerated. He continues to have hyperglycemia despite the addition of insulin lispro.  During his diabetes education visit today, he shared that he has not been taking his mealtime insulin lispro because he does not want to inject it in front of his grandchildren, who live with him.  He feels overwhelmed by these additional injections but wants to get his blood glucose levels under better control so he can have the energy to play with his grandchildren and avoid losing his eyesight like his mother did.

As the diabetes care and education specialist, which of the following would be the most appropriate first step in addressing R.S.’s concerns? 

  1. Stress with R.S. the importance of never missing his meal time lispro to prevent diabetes-related complications.
  2. Using open-ended questions, explore R.S.’s routine, stressors, and support systems to understand the barriers to his insulin use.
  3. Recommend R.S. switch to another non-insulin medication to make his regimen easier for him to manage.
  4. Since it appears R.S. did not understand how to take his insulin lispro, write out step-by-step instructions on how to take the insulin.

Getting to the Best Answer

If you are thinking about taking the certification exam, this practice test question will set you up for success. Test writers anticipate possible answers based on the details in the question. They will wave those “juicy answers” right under your nose. Your job is to weed through the particulars, pluck out the most important elements and choose the BEST answer.

Answer A is incorrect: 1% chose this answer, “Stress with R.S. the importance of never missing his meal time lispro to prevent diabetes-related complications.” R.S. is aware that his glycemic control is important, and he is already aware of the risk of diabetes-related complications. Counseling him on this would not help him be successful with his insulin management.  

Answer B is correct: 96% chose this answer, “Using open-ended questions, explore R.S.’s routine, stressors, and support systems to understand the barriers to his insulin use.” R.S. is struggling with barriers to successful insulin management.  A holistic approach would be to ask open-ended questions about his current routine, stressors, and support systems to gain a better understanding of these barriers. This information can lead to a personalized plan of care to help improve glycemic control. 

Answer C is incorrect: 2% chose this answer, “Recommend R.S. switch to another non-insulin medication to make his regimen easier for him to manage.” He has already attempted other non-insulin therapies, and these were either ineffective or not tolerated. Changing his regimen would not be successful at improving his glycemic control and quality of life.

Answer D is incorrect: 1% chose this answer, “Since it appears R.S. did not understand how to take his insulin lispro, write out step-by-step instructions on how to take the insulin.” R.S. appears to understand how to take his insulin lispro at meals. Writing out the instructions would not improve his situation. It is not a lack of knowledge, but the multiple barriers in his life that are keeping him from being able to implement this new medication regimen.  

We hope you appreciate this week’s rationale! Thank you so much for taking the time to answer our Question of the Week and participate in this fun learning activity!

Invite a colleague to our DiabetesEd Seminar in San Diego and get $75 off each registration.

Use code FriendDiscountSD during check out to save. 

Join us live in San Diego October 22nd – 23rd, 2025 for our upcoming

DiabetesEd Training Seminar

30+ CEs with Expanded Accreditation!

Join our expert team for engaging, interactive sessions that bring the ADA Standards of Care to life—covering medications, behavior change, technology, and more. Ideal for CDCES or BC-ADM exam prep, this course also includes a 4-hour Virtual Medical Nutrition Therapy Toolkit and bonus content that also meets CDCES renewal requirements.

Program Objectives:

Upon completion of this activity, participants should be able to:

  • Describe the current ADA Standards for diagnosis, goals, and person-centered diabetes management across the lifespan. 
  • Demonstrate insulin pattern management and dosing strategies in clinical scenarios.
  • Implement timely screening and risk reduction strategies for microvascular and cardiovascular complications.  
  • Incorporate behavior change techniques and medical nutrition therapy to support people with diabetes self-management and lifestyle adjustment.  

Expert Faculty:

Diana Isaacs, PharmD, BCPS, BCACP, CDCES, BC-ADM, FADCES, FCCPCES

Smiling woman in white blazer and lavender blouse

Beverly Thomassian, RN, MPH, CDCES, BC-ADM

Faculty Bios & Disclosures

Our expert team transforms complex diabetes science into clear, practical insights—keeping it real, engaging, and fun!

Program Faculty Disclosures:

Partners for Advancing Clinical Education (Partners) requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Partners policies. Others involved in the planning of this activity have no relevant financial relationships.

Faculy Bios & Disclosures:

Coach Beverly Thomassian RN, MPH, CDCES, BC-ADM – CEO of DiabetesEd Services

Disclosures: 

Beverly Thomassian has no financial disclosures

Bio:

Author, Nurse, Educator, Clinician, and Innovator, Beverly has specialized in diabetes management for over twenty years. As president and founder of Diabetes Education Services, Beverly is dedicated to providing compassionate and evidence based diabetes education and improving the lives of those with diabetes.

PicsArt_04 03 11Diana Isaacs, PharmD, BCPS, BCACP, CDCES, BC-ADM, FADCES, FCCPCES 

Disclosures:

Dr. Diana Isaacs has the following relevant financial relationships:

  • Consultant, advisor, and speaker for Abbot Labratories, Dexcom, Medtronic, Insulet, Lilly, Cequr, Sanofi, and Undermyfork
  • Board member at Association for Diabetes Care and Education Specialists

Bio:

Diana Isaacs was awarded 2020 ADCES Diabetes Educator of the Year for her educational platform promoting the use of CGM for people with diabetes and other innovations.  She serves in leadership roles for several pharmacies and diabetes organizations. She has numerous diabetes publications and research projects with a focus on medications, CGM and diabetes technology.

For the past three year, Dr. Isaacs has served as a contributing author for the 2023 ADA Standards of Care.

As the Program Coordinator and clinical pharmacist specialist in the Cleveland Clinic Diabetes Center, Dr. Isaacs brings a wealth of clinical knowledge combined with extensive research and speaking experience to this program. 

Activity Start and End Date: 10/22/25 – 10/23/2025

Estimated time to complete the activity: 15 hours and 30 minutes

_____________________________________

Jointly provided by Partners for Advancing Clinical Education and Diabetes Education Services



Joint Accreditation Statement:

 In support of improving patient care, this activity has been planned and implemented by Partners for Advancing Clinical Education (Partners) and Diabetes Education Services. Partners is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Education:

Partners designates this enduring material for a maximum of 15.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development:

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 15.50 contact hours.

Pharmacy Continuing Education:

Partners designates this continuing education activity for 15.50 contact hour(s) (1.550 CEUs) of the Accreditation Council for Pharmacy Education.
(Universal Activity Number – JA4008073-9999-25-206-L01-P)
Type of Activity: Application

For Pharmacists: Upon successfully completing the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 4 weeks.

Dietitian Continuing Education:

This program offers 15.50 CPEUs for dietitians.

Interprofessional Continuing Education:

This activity was planned by and for the healthcare team, and learners will receive 15.50 Interprofessional Continuing Education (IPCE) credit for learning and change.

For additional information about the accreditation of this activity, please visit https://partnersed.com.

The use of DES products does not guarantee the successful passage of the certification exam. CBDCE and ADCES do not endorse any preparatory or review materials for the CDCES or BC-ADM exams, except for those published by CBDCE & ADCES.

Download Free Diabetes Cheat Sheets!

Get the Tools You Need for 2026

Attention Diabetes Healthcare Professionals: Our Diabetes Cheat Sheet Resource Page Is Updated for 2026!

If you’re a busy diabetes healthcare professional, you want tools that help you deliver excellent, evidence-based care—without spending hours digging for information. That’s exactly why we created our Diabetes Cheat Sheet Resource Page, and we’re excited to share that it’s been updated with new additions for 2026.

You can download these free clinical and teaching cheat sheets directly from our website or through the CDCES Coach App. To make your life easier, we’ve reorganized everything by category and alphabetically, so you can quickly find exactly what you need—right when you need it.

Clinical Cheat Sheets: Evidence at Your Fingertips

The first section focuses on concise, evidence-based clinical summaries drawn from the American Diabetes Association Standards of Care and current research. These resources are ideal for:

  • Day-to-day clinical decision-making
  • Teaching colleagues and learners
  • Preparing for certification exams

Some of our most popular Clinical Cheat Sheets include:

  • Indications for GLP-1/GIP receptor agonists for diabetes, weight management, and cardiovascular disease
  • Lipid & Hypertension Medications Cheat Sheet
  • Neuropathy Treatment in Diabetes
  • Screening and Diagnostic Criteria for diabetes

Patient Education Resources You Can Share with Confidence

The next section includes ready-to-use handouts designed for people living with diabetes. Many are available in both English and Spanish, and several allow you to add your own logo or tailor the content to better serve your population.

A highlight of this section is the new “Keeping Healthy with Diabetes” sheets. These were personally created by Coach Beverly as teaching tools for community classes and for the people she serves in a rural health clinic. They clearly summarize:

  • What a diabetes diagnosis means
  • Key goals of diabetes care
  • Practical, easy-to-understand health messages

Perfect for printing, sharing, and using in real-world conversations.

Technology, Nutrition, Apps & Carb Counting Support

You’ll also find dedicated sections on:

  • Diabetes technology (including tools to evaluate accuracy)
  • Nutrition resources
  • Helpful diabetes apps
  • Carbohydrate counting tools, which are especially valuable for those preparing for CDCES or BC-ADM certification

Whether you’re caring for people with diabetes, teaching others, or preparing for an exam, these updated resources are designed to save you time, reduce overwhelm, and support best-in-class care.

Love Cheat Sheets? You can Access on New CDCES Coach App!

Level 2 | ADA Standards of Care Complete Review

Join us live on January 29th, 2026 at 11:30 AM PST!

NEW CDCES Coach App

Download for FREE on the Google Play Store or Apple Store!

Meds PocketCard Refresh for 2026!

Fresh updates. Clear comparisons. Even more clinical confidence.

You are going to love the latest updates to our Medication PocketCards—designed to help you make quick, informed decisions at the point of care.

GLP-1 & GIP Medications: Now Easier to Compare Than Ever

Our GLP-1 & GIP Meds PocketCard now includes two distinct versions—one for diabetes and one for weight management—so you can compare therapies at a glance.

Each version clearly outlines:

  • Approved indications
  • Medication action
  • Efficacy
  • Common side effects

This side-by-side approach makes it easier to individualize treatment decisions based on a person’s health profile, age, and comorbidities.

Oral Semaglutide for Weight Loss—Now Included

Big news in the GLP-1 world! Semaglutide is now available as an oral formulation for weight loss, and we’ve added it to the PocketCard.

  • Rybelsus® remains the oral option approved for diabetes
  • Oral semaglutide for weight loss is FDA-approved and included on the updated card
  • Both formulations are approved to reduce cardiovascular risk

Just like Rybelsus, oral semaglutide for weight loss:

  • Must be taken on an empty stomach
  • With a small sip of water
  • At least 30 minutes before food, beverages, or other medications

Good-Bye to Exenatide XR

It’s the end of an era. Exenatide XR (Bydureon®, Bcise®) has been discontinued.

The only remaining option is generic exenatide, administered twice daily—still available and noted on the updated PocketCard.

TZDs: A Farewell and a Comeback

We say goodbye to rosiglitazone and welcome a renewed appreciation for pioglitazone (Actos®).

Pioglitazone:

  • Improves insulin resistance
  • Lowers free fatty acids
  • Is now indicated for hepatic steatosis or for individuals who have experienced a stroke.

Research led by Dr. Ralph DeFronzo demonstrates that pioglitazone can shift fat from visceral to subcutaneous depots, improving metabolic health and liver outcomes.

Clinical pearls included on the card:

  • Start low (15 mg) and titrate slowly
  • Monitor for fluid retention and weight gain
  • Check ankles and assess heart failure risk
  • Avoid in individuals with CHF or high fracture risk

Importantly, pioglitazone is also indicated for people with prediabetes or diabetes who have experienced a stroke, as it significantly reduces the risk of recurrent stroke.

DPP-4 Inhibitors: A Smaller Role

DPP-4 inhibitors continue to decline in use due to lower efficacy and higher cost, and both alogliptin and sitagliptin carry an increased risk of hospitalization for heart-failure .

That said, generic sitagliptin is once again available, so we’ve added it back to the PocketCard in the DPP-4 category—clearly labeled to support informed prescribing.

Give Feedback - Get FREE PocketCard 💜 We Want to Hear From You

  • What do you think of the 2026 PocketCard updates?
  • How do these cards support your clinical decision-making?

Please Share your thoughts and observations with us!  Get a FREE PocketCard in the mail.

Your feedback helps us keep these tools practical, relevant, and clinician-approved.

Learn More About Meds With Upcoming Courses

ADA Standards of Care Complete Review

Join us live on January 29th, 2026 at 11:30 AM PST!

Virtual DiabetesEd Training Conference

Join us on April 15th-17th, 2026!

Rationale of the Week | Teens’ A1C Climbs After Starting CGM

For last week’s practice question, we quizzed participants on SJ having questions about their insulin pen, and what would be the best response. % of respondents chose the best answer. We want to clarify and share this important information, so you can pass it on to people living with diabetes and your colleagues, plus prepare for exam success!

Before we start though, if you don’t want any spoilers and haven’t tried the question yet, you can answer it below: Answer Question

Lightbulb and text: Rationale of the Week

Katie is a 14-year-old living with type 1 diabetes since age 10. She uses multiple daily insulin injections (MDI) therapy to manage her diabetes and started using a continuous glucose monitor (CGM) 3 months ago at the recommendation of her endocrinology team. Her A1c has increased to 9.2% since starting CCM technology.

Her mother reports that Katie has episodes of prolonged hyperglycemia when she is away from home. When at home, her mother will remind Katie to bolus based on the alerts she gets on the CGM share app. Katie reports she mutes alarms and alerts because she doesn’t want her classmates to hear them, afraid they will judge her. When you ask if she has uploaded her data to the school nurse or her endocrinology team she says, “The app is really confusing.” Her mother is frustrated with Katie for not paying attention to the CGM, saying, “She can text her friends without any problem; I don’t know why she struggles with the CGM”.

As the diabetes healthcare provider, how can you support Katie in improving her glycemic control?

  1. Turn on her CGM alarms but increase the high alarm so she doesn’t get as many hyperglycemia related alerts.
  2. Show her step-by-step how to use the app and how to troubleshoot the alerts and alarms.
  3. Have the school nurse monitor her CGM trends when Katie is at school, since her mom monitors the CGM trends when she is at home.
  4. Email Katie’s mother once a week for updates to make sure she is monitoring CGM trends.

Getting to the Best Answer

If you are thinking about taking the certification exam, this practice test question will set you up for success. Test writers anticipate possible answers based on the details in the question. They will wave those “juicy answers” right under your nose. Your job is to weed through the particulars, pluck out the most important elements and choose the BEST answer.

Answer A is incorrect: % chose this answer, “Turn on her CGM alarms but increase the high alarm so she doesn’t get as many
hyperglycemia related alerts.” Helping Katie turn on and increasing her high alarm will not help
improve her glycemic control.

Answer B is correct: % chose this answer, “Show her step-by-step how to use the app and how to troubleshoot the alerts and alarms.” Guiding Katie through the CGM app and its functions helps her ask questions, resolve issues, and better monitor her glycemic control.

Answer C is incorrect: % chose this answer, “Have the school nurse monitor her CGM trends when Katie is at school, since her mom
monitors the CGM trends when she is at home.” Asking the school nurse to monitor CGM data while Katie is at school is not helping to improve Katie’s self-management skills.

Answer D is incorrect: % chose this answer, “Email Katie’s mother once a week for updates to make sure she is monitoring CGM
trends.” Emailing Katie’s mother does not help improve Katie’s CGM self-monitoring skills or her confidence level with the CGM app.

We hope you appreciate this week’s rationale! Thank you so much for taking the time to answer our Question of the Week and participate in this fun learning activity!

Virtual DiabetesEd Training Conference

April 15th-17th, 2026

Gain fresh insights, practical tools, and a deeper understanding of the latest in person-centered diabetes care. Our expert team brings the ADA Standards of Care to life—covering medications, behavior change, technology, and more!

If you’re preparing for the CDCES or BC-ADM exam, this conference, paired with a handful of free bonus courses, serves as the ideal study companion! Plus, this content counts toward the ADA Standards requirements for CDCES Renewal.

With interactive co-teaching, we keep sessions engaging, relevant, and fun. 

Let’s learn and grow together!

Course credits through AMA PRA Category 1 Credits™, ACPE, ANCC, and CDR!

Program Objectives:

Upon completion of this activity, participants should be able to:

  • Describe the current ADA Standards for diagnosis, goals, and person-centered diabetes management across the lifespan. 
  • Demonstrate insulin pattern management and dosing strategies in clinical scenarios.
  • Implement timely screening and risk reduction strategies for microvascular and cardiovascular complications.  
  • Incorporate behavior change techniques and medical nutrition therapy to support people with diabetes self-management and lifestyle adjustment.  

Rationale of the Week | CS’s A1C Climbs After Experiencing Distress

For last week’s practice question, we quizzed participants on CS’s A1C climbing after experiencing distress. % of respondents chose the best answer. We want to clarify and share this important information, so you can pass it on to people living with diabetes and your colleagues, plus prepare for exam success!

Before we start though, if you don’t want any spoilers and haven’t tried the question yet, you can answer it below: Answer Question

Lightbulb and text: Rationale of the Week

CS is a 42-year-old with type 1 diabetes for just over 18 years. In the past year, their A1C changed from 7.4% to 9.1%, and weight increased by 20 pounds. Review of CGM data suggests missed insulin boluses more than 7 times per week, and discussion with CS reveals missed clinic visits due to feeling “burned out”. They score in the moderate range on the Diabetes Distress Scale.

Based on the ADA 2026 Standards of Care, which of the following is the most appropriate next step?

  1. Partner with CS to reduce missed boluses and reassess in 3 months.
  2. Simplify regimen to support current state of diabetes distress.
  3. Refer to a qualified behavioral health professional for evaluation and treatment.
  4. Recommend referral to MNT for a structured weight-loss program.

Getting to the Best Answer

If you are thinking about taking the certification exam, this practice test question will set you up for success. Test writers anticipate possible answers based on the details in the question. They will wave those “juicy answers” right under your nose. Your job is to weed through the particulars, pluck out the most important elements and choose the BEST answer.

Answer A is incorrect: % chose this answer, “Partner with CS to reduce missed boluses and reassess in 3 months.” Answer A is incorrect as it is not the best answer. While reducing missed boluses and optimizing insulin therapy are essential to support A1c reduction, this intervention alone does not address the likely underlying psychological barriers to self-management.

Answer B is incorrect: % chose this answer, “Simplify regimen to support current state of diabetes distress.” Answer B is incorrect; it is not the best answer. While simplifying insulin dosing may be supportive in some cases, without addressing the underlying diabetes distress it is unlikely to achieve sustained improvement.

Answer C is correct: % chose this answer, “Refer to a qualified behavioral health professional for evaluation and treatment.” Answer C is correct. The 2026 ADA Standards of Care recommends a referral to a qualified behavioral health professional for evaluation and treatment when diabetes distress, burnout, reduced engagement in diabetes management or other psychosocial factors are impacting self-care and glycemic targets. ¹

Answer D is incorrect: % chose this answer, “Recommend referral to MNT for a structured weight-loss program.” Answer D is incorrect. Focusing solely on weight loss does not address the primary psychosocial barriers and weight gain may be a symptom of underlying behavioral health needs. Evaluation and treatment from a behavioral health provider would be the most appropriate next step.

We hope you appreciate this week’s rationale! Thank you so much for taking the time to answer our Question of the Week and participate in this fun learning activity!

Learn More With Our Upcoming Webinars

Level 2 | ADA Standards of Care Complete Review

Join us live on January 29th, 2026 at 11:30 AM PST!

Level 2 | Improving Care and Promoting Health

Join us live on February 10th, 2026 at 11:30 AM PST!

January 2026 eNews

Happy January!💚

Greetings, wonderful healthcare colleagues!

You are going to love all the updates to our cheat sheets, online university courses, and PocketCards.

Coach Beverly has been excitedly scanning the 2026 ADA Standards to discover updates and advances in diabetes care. She and her team are hustling to integrate these new findings across our platforms, including the CDCES Coach App, handouts, courses, and web content, so that you can access the latest information with confidence.

In our first newsletter of 2026, we are excited to share that we have made significant changes to our Medication PocketCards in the GLP-1/GIP RA section. Now included are the diabetes and weight-loss versions of this popular medication class, with indications for each. You can compare and contrast at a glance. Download your free version and read more below.

Our library of Cheat Sheets is updated and includes a few new additions! These sheets are available on our website and the CDCES Coach App for easy access, with the option to download and share with your colleagues and people living with diabetes alike.

Christine Craig, MS, RD, CDCES, explores her experience with a client who arrived at her office distraught and struggling with the loss of his lifelong partner. Pass the tissues.

Our Tech contributor, Dr. Beattie, provides a summary of red flag statements that may indicate a person is experiencing barriers to effectively using technology in their day-to-day management.

We encourage you to test your knowledge with our Question and Rationale of the Week. January kicks off our Level 1 Fundamental Series, followed by our annual ADA Standards of Care update on January 29th and Level 2 Mastery Course Series in February. We hope to see you there!

Here is to a 2026 filled with self-compassion and moments of awe.

Coach Beverly, Bryanna, Astraea & Katarina

Order 2026 ADA Standards Book + Webinar!

Upcoming Free Webinars

Join us Jan. 27th, 2026, at 11:30 AM PST

Join us Feb. 5th, 2026 at 11:30 AM PST

Upcoming CE Course Series

6 Session Series starts on Jan. 7th, 2026!

Join us on Jan. 29th, 2026, @ 11:30 AM PST!

14 Session Series starts on Jan. 29th, 2026!

2 Day Virtual Conference April 15th-17th, 2026!